Full dataset

This dataset can be used to reproduce results in the TwinC manuscript. Please download this data in the same folder as the TwinC paper repository. We have submitted our training datasets to zenodo.org/records/15802811. The datasets are divided into three parts:

Data

The sequence data can be downloaded using:

cd twinc-paper/
wget https://zenodo.org/records/15802811/files/TwinC_data_resources_V1.tar.gz

After downloading, you can uncompress the file, and it will populate the data folder. 

tar -xvzf TwinC_data_resources_V1.tar.gz

This dataset contains:

  1. hg38.no_Y_MT.fa: Fasta file for the human genome containing chromosomes 1-22 and X.

  2. hg38.no_Y_MT.fa.fai: Index for the fasta file.

  3. hg38.no_Y_MT.memmap: One-hot-encoded memory map for the human genome.

A -> [1, 0, 0, 0]
C -> [0, 1, 0, 0]
G -> [0, 0, 1, 0]
T -> [0, 0, 0, 1]
  1. gene_tpm_2017-06-05_v8_heart_left_ventricle.gct: TPMs for genes in the heart's left ventricle from the GTEX.

Labels

Labels for training, as well as intermediate results for reproducing the figures, can be downloaded using:

cd twinc-paper/
wget https://zenodo.org/records/15802811/files/TwinC_label_resources_V1.tar.gz

After downloading, you can uncompress the file, and it will populate the results folder. 

tar -xvzf TwinC_label_resources_V1.tar.gz

Models

You can download the pretrained models using:

cd twinc-paper/
wget https://zenodo.org/records/15802811/files/TwinC_models_V1.tar.gz

After downloading, you can uncompress the file, and it will populate the models folder. 

tar -xvzf TwinC_models_V1.tar.gz